This thesis has been focused around the Diels Alder reaction with the goal to design an enzyme catalyzed reaction pathway. To achieve this goal computer aided enzyme design was utilized. Common traditional methods of computational chemistry (B3LYP, MP2) do not do well when calculating reaction barriers or even reaction energies for the Diels Alder reaction. New calcu- lation methods were developed and tested. This was the focus of the first part of the thesis, by choosing a small system, extensive and heavy calculations could be done with CBS-QB3.

This thesis has been focused around the Diels Alder reaction with the goal to design an enzyme catalyzed reaction pathway. To achieve this goal computer aided enzyme design was utilized. Common traditional methods of computational chemistry (B3LYP, MP2) do not do well when calculating reaction barriers or even reaction energies for the Diels Alder reaction. New calcu- lation methods were developed and tested. This was the focus of the first part of the thesis, by choosing a small system, extensive and heavy calculations could be done with CBS-QB3.

Since 1865 when Lubbock introduced the Palaeolithic and Neolithic to the surrounding archaeological world there has been an apparent problematic in how we define the different periods. When the Mesolithic age was introduced to fill the hiatus between the Palaeolithic and Neolithic, the problematic became even more noticeable. By examine different subjects which distinguish the different periods I wish to highlight the problematic in viewing them as characteristics. The problem lies in seeing the characteristics as defining only one period when they actually can be seen in two or all three of the periods. I then tried to give the different period's new better suited definitions.

This study examines how professional social workers relate to problematic computer and video gaming as an addiction. It is a qualitative interview study aimed to describe and analyze how professional social workers, who in some way work with problematic computer gaming, relate to the player?s problems in terms of a concept of dependency. The theoretical approach is based on social constructivist theories of discourses, normality, the definition of dependency and diagnoses. The study was conducted through five qualitative half structured definition interviews with professional social workers that work directly or comes in contact with problematic computer gaming.

Vegetation is a much appreciated element in our outdoor environment that has many advantages as well for the climate as for people?s health. However in some types of environments vegetation may be problematic. Especially in urban areas with limited space, solid surfaces, pollutions, and warm and dry climate. In these environments vegetations may have difficulty surviving and moreover it may have a negative impact on the environment around it.

This student report is about canine atopic dermatitis It includes a description of the immunologic mechanisms and how the reaction affects the body. The symptoms are various, most common is pruritus, erythema and alopecia and directly associated with the immunologic reaction. The diagnostic process includes symptoms, physical findings, differential diagnosis, intradermal test and serological test. The options of treatment are several and vary for each patient. The report includes hyposensitization, medical treatment such as corticosteroids, antihistamin and cyclosporine, topical treatment, fatty acid supplements and environmental treatment. The prognosis is individual for each patient due to their different response to the treatment. It may take a while to find the right combination of treatments to achieve satisfactory control of the disease..

The purpose of this study is to examine the capital market reaction generated by layoff announcements. The study takes place in Sweden and tests 138 news concerning layoffs which are categorized according to a content analysis. They are divided as: positive or negative news. The layoffs are also divided into three subgroups with varying sizes: 0,98 percent or less, between 0,99 and 4,49 percent or 4,5 percent or larger. The study uses an event study method to measure the reaction of the capital market.

This thesis adresses the subject of stormwater management and the problematic with stormwatermanagment and landuse in the compact city. The thesis research different solutions in stormwater managment and how to implement them in the context of the compact city. And at the same time preserve and make good recreaational places and keep quality green land per capita. The thesis also analyses risks and problems that could effect the environment with focus on stormwater managment and hov to minimize these problematic factors an create a good environment. In an urban context where the water has a natrual place, and is used as a asset.

The aim of this master thesis is to examine which criteria are generally used to guide pub­lic librarians in their acquisitions' decision. The study went ahead in France, principally at La Bibliotheque municipale de Lyon. It also includes a view of some special library services in the social field.Twenty persons were interviewed and an attempt was made to divide their answers into three sections: acquisition routines and criteria for media purchase, how to receive the library visi­tors and their influence on the acquisitions, and, finally, the librarians' own opinions on the matter. One important question was whether censorship is applied and in that case, would it be a deliberately way of acting or rather a spontaneous reaction, more or less unconscious.Censorship in real or manifested through a self-preservative reaction turned out to be a factor closely dependant on the library's financial situation. Many librarians affirmed they would find useful some kind of a written practical library acquisition policy..

Purpose: The purpose of this thesis is to investigate whether abnormal stock returns could be identified as a result of a layoff announcement during weak economy.Method: An event study methodology.Theory: Efficient market hypothesis, signal theory.Empirical results: Quantitative data from observations of stock prices in thirty two companies listed on the Nasdaq OMX Stockholm, in the period 2008 -2012.Conclusion: The results indicate that the market reaction was negative because there were negative abnormal returns on the Stockholm Stock Exchange during the period 2008-2012 in connection with the layoff announcements. The market reaction was milder when staff reductions were carried out as a result of a restructuring and stronger when staff reductions were carried out as part of a cost reduction program.The layoff announcements elicited different market reactions depending on the company's industry affiliation. The most negative reaction was in the Healthcare industry. Negative abnormal returns were lower in industries Industrials, Consumer Services and Consumer Goods. There were no abnormal returns for shares of companies in the industry Financials.

This study was performed in order to evaluate if the method of collecting uterine secretion by the tampon-method is representative for use in studies of uterine secretions in mares. Uterine secretion collected by tampon in six mares was compared with secretion collected by aspiration, regarded to be a native sample, at the Institution of Obstetrics and Gynaecology, SLU, Uppsala. Proteinanalysis was made at the Department of Farmaceutic Bioscience, toxicological unit, Uppsala University. Cytological smears and ultrasonography was used to assess if the tampon had caused an inflammatoric reaction that could influence the protein content of the samples. The results suggest that the tampon and aspirat method do not differ when it comes to proteinconcentration, but the distribution of proteins differ between these different collection methods. This difference could not likely be explained by means of proteins due to an inflammatory reaction from the tampon, since neither the cytological nor the ultrasonographical examination gave any indications of inflammation.

The aim of this study is to examine how the public responds to the journalists? use of subjectivity in the reporting of broadcasting news. The investigation is a qualitative study based on nine interviews with respondents in ages of 21 to 25 from different parts of Sweden. After showing five examples of news reporting with a subjective approach, the respondents gave their look on the use of subjectivity. The theoretical frame of the investigation is founded on the theory of framing (de Vreese, 2005; Entman, 1993) and the discussion concerning the terms objectivity and subjectivity (e.g.

Through the notions of the untimely (l'intempestif) and untimeliness (intempestif) this paper seeks to gain a better understanding of the problematic surrounding and determining the concept of time in Deleuze. By tracing Deleuze's development of the concept of the untimely through Nietzsche and Kant, we are allowed to concretize the concept of time as pertaining to an experience of modernity (modern life), thus enabling us to better determine the place it holds within the philosophy of Deleuze itself - as a constitutive and productive problematic relating directly to the activity of thinking and being philosophically..

Tractors of today come equipped with a CAN-system. A CAN-system sends information from sensors to electronic control units who process the signals. The sensors measure several interesting parameters such as force, pressure and speed for various components of the tractor. This thesis discuss a force sensor which is placed in the pivot of the tractors three point linkage, the sensor measure the horizontal reaction force from the load that the tractor is exposed to. Signals from this sensor can be used to measure the force from any implement that the tractor is exposed to during an operation.

In this study I investigated whether the strength in the manual response for emotional and neutral stimulus search arrays can explain some of the difference in reaction times (RT:s) for emotional stimuli, or not. Earlier, perceptual, cognitive and attentional processes has mostly been used to explain the variance in RT:s. Thirtythree individuals were asked to, as fast as possible, detect a target picture among distractor pictures in 3 rows x 4 columns arranged search arrays. The pictures were categorized in fear relevant animals (snake, spider) and neutral animals (cat). The results showed, more correct responses for cat target.